and Native cultures who worked cooperatively, respecting each other's traditions and customs.
William Penn negotiated with the Native people in southeastern Pennsylvania for territory to settle on. After the Revolution, Chief Cornplanter of the Seneca nation invited Quakers to teach the Seneca people enough of Euroamerican culture to adjust to living among them.
Prior to the American Revolution, Quakers living among Native people had such good relationships with them that when the Quakers needed to travel to attend to business, e g. picking up supplies from a distant trading post or village, they left their children in the care of a Native family until they returned. During the Revolution, when some of the Haudenosaunee tribes joined the British side, they had an agreement with Quakers and other people with whom they had good relationships that they would not harm their land, buildings, or people. Quakers used a piece of cloth to designate their homes and property.
But, eagerness of later Americans and immigrants to have farms, ranches, and villages in the West, spurred on by land speculators, created hordes of people flooding into Native lands and ignoring treaty agreements.
Manifest Destiny did not begin with the westward movement to lands beyond the Mississippi. It began with the earliest Puritan and Pilgrim colonists. They believed that they had a mission to occupy all of America to Christianize it. They compared America to ancient Canaan and themselves to the Israelites conquering the land in a covenant with God. That's how the city of New Canaan, CT got its name.