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[No Vested Interest]

6. You are correct that drug therapy for mental issues is the first line

of defense.
You are also correct that one must give any prescribed drugs a fair chance to do their work.
That some do not correct the problem is known, and even the trained psycho-pharmacist may not figure out the answer for some individuals.
Hanging in and not giving up hope when one wants to throw in the towel is the most likely way to health.