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douglas9

(5,208 posts)
Thu Oct 16, 2025, 07:30 AM Thursday

New Alzheimer's Treatment Clears Plaques From Brains of Mice Within Hours

Scientists have repaired a natural gateway into the brains of mice, allowing the clumps and tangles associated with Alzheimer's disease to be swept away.

After just three drug injections, mice with certain genes that mimic Alzheimer's showed a reversal of several key pathological features.

Within hours of the first injection, the animal brains showed a nearly 45 percent reduction in clumps of amyloid-beta plaques, a hallmark of Alzheimer's disease.

The mice had previously shown signs of cognitive decline, but after all three doses, the animals performed on par with their healthy peers in spatial learning and memory tasks. The benefits lasted at least six months.

https://www.sciencealert.com/new-alzheimers-treatment-clears-plaques-from-brains-of-mice-within-hours

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multigraincracker

(36,562 posts)
1. My dad use to say "what ever kills you, they will
Thu Oct 16, 2025, 08:11 AM
Thursday

find a cure five years later”.
He was a great scientist.

Bernardo de La Paz

(59,744 posts)
4. co-led by scientists at Inst. for Bioengineering of Catalonia (IBEC) & West China Hospital Sichuan Univ (WCHSU). . nt
Thu Oct 16, 2025, 08:33 AM
Thursday

international team of researchers, co-led by scientists at the Institute for Bioengineering of Catalonia (IBEC) and the West China Hospital Sichuan University (WCHSU).

Bengus81

(9,523 posts)
6. Any break through of anything will always be available for the rich
Thu Oct 16, 2025, 09:02 AM
Thursday

no matter what that idiot does.

3Hotdogs

(14,725 posts)
8. My mom was a fan of articles, "What your Dr. doesn't want you to know...."
Thu Oct 16, 2025, 09:16 AM
Thursday

She made it to 98 so maybe she was on to something.

KS Toronado

(21,633 posts)
13. My mom made it to 96
Thu Oct 16, 2025, 10:39 AM
Thursday

and she also questioned doctors and took a lot of over-the-counter vitamins & meds.

dooner

(1,226 posts)
14. UCSF (University of California, San Francisco) just cut Alzheimer's Research
Thu Oct 16, 2025, 02:23 PM
Thursday

UCSF does a lot of medical research and clinical trials in Northern California. Research funding cuts were announced yesterday, including Alzheimer's research.

https://www.sfgate.com/bayarea/article/ucsf-staff-cuts-deepen-threaten-drug-research-21098563.php

NNadir

(36,785 posts)
3. I have worked with a scientific team addressing this disease as...
Thu Oct 16, 2025, 08:20 AM
Thursday

...an inflammatory syndrome, certainly related to the described mechanism.

This said the history of Alzheimer's treatments and theory are littered with false starts and even fraud, the famous Lesne case being the most famous, again involving mice, albeit with doctoring images of Western blots.

This is not to say this work is suspect; it may be very good, even a "breakthrough," to use that oft abused word, but it will need to be shown to be replicable in many labs to confirm the finding.

As science in this country is now subject to willful vandalism by ignoramuses, the prospect does not look promising.

JustABozoOnThisBus

(24,429 posts)
11. RFK's method for removing plaque from brains: Mental Floss.
Thu Oct 16, 2025, 10:11 AM
Thursday

in one ear, out the other, sawing motion, easy-peasey. Or, just use worms.

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